Which of the following drug characteristics results in a smaller drug volume of distribution:

a) Nonpolar drugs

b) Lipophilic drugs

c) Small molecular size

d) None of the above

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Answer

Answer d.

Lipophilic and nonpolar drugs as well as drugs of smaller molecular size tend to have increased (not decreased) volumes of distribution.


Notes


This question originally printed in the Pediatric Anesthesiology Review Topics kindle book series, and appears courtesy of Naerthwyn Press, LLC.

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