TYK152

ε-Aminocaproic acid (EACA) and tranexamic acid reduce surgical bleeding due to:

a) Prevention of fibrin degradation

b) Enhanced platelet function

c) Replacement of depleted coagulation factors

d) Antagonism of antithrombin activity

e) Stimulation of tissue factor production

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Answer

Answer a.

ε-Aminocaproic acid (EACA) and tranexamic acid are lysine analogues that bind to plasminogen and plasmin, interfering with the interaction of plasmin with fibrin and preventing fibrin degradation.

Notes

This question originally printed in the Pediatric Anesthesiology Review Topics kindle book series, and appears courtesy of Naerthwyn Press, LLC.

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