TYK305

Which of the following statements about antidiuretic hormone is TRUE?

a) Nausea is a potent inhibitor of ADH release.

b) ADH increases permeability of free water in renal principle cells via insertion of aquaporin protein.

c) ADH causes vasodilation of vascular smooth muscle via V1 receptors.

d) Decreased serum osmolarity stimulates ADH release.

e) ADH is produced in the ventrolateral nucleus of the hypothalamus.

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Answer

Answer b. ADH stimulates aquaporin insertion into the apical cell membranes of the renal principle cells; aquaporins are water channels that allow reabsorption of water in the distal tubules and collecting ducts of the nephron. Nausea stimulates ADH release, and decreased osmolarity inhibits ADH release from the supraoptic nucleus of the hypothalamus. The effect of ADH on vascular smooth muscle is vasoconstriction.

Notes

This question originally printed in the Pediatric Anesthesiology Review Topics kindle book series, and appears courtesy of Naerthwyn Press, LLC.

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