TYK295

The causes of renal failure leading to transplantation in the pediatric population, in order of occurrence, are:

a) Diabetic nephropathy, FSGS, IgA (Berger’s) nephropathy, reflux nephropathy

b) Obstructive nephropathy, FSGS, congenital dysplasia/aplasia, hemolytic uremic syndrome

c) Congenital dysplasia/aplasia, obstructive nephropathy, FSGS, diabetic nephropathy

d) Polycystic kidney disease, obstructive nephropathy, FSGS, congenital aplasia/dysplasia

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Answer

Answer c. While diabetic and hypertensive nephropathies are common causes of ESRD requiring transplant in the adult population, congenital and obstructive uropathies are more common in pediatrics, with FSGS as the third leading diagnosis in those receiving transplant. Together, these three causes account for greater than 40% of cases of pediatric ESRD. Diabetic nephropathy accounts for only 0.1% of causes leading to pediatric kidney transplant.

Notes

This question originally printed in the Pediatric Anesthesiology Review Topics kindle book series, and appears courtesy of Naerthwyn Press, LLC.

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