The causes of renal failure leading to transplantation in the pediatric
population, in order of occurrence, are:
a) Diabetic nephropathy, FSGS, IgA (Berger’s) nephropathy, reflux nephropathy
b) Obstructive nephropathy, FSGS, congenital dysplasia/aplasia, hemolytic
uremic syndrome
c) Congenital dysplasia/aplasia, obstructive nephropathy, FSGS, diabetic
nephropathy
d) Polycystic kidney disease, obstructive nephropathy, FSGS, congenital
aplasia/dysplasia
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Answer
Answer c. While diabetic and hypertensive nephropathies are common causes of
ESRD requiring transplant in the adult population, congenital and obstructive
uropathies are more common in pediatrics, with FSGS as the third leading
diagnosis in those receiving transplant. Together, these three causes account for
greater than 40% of cases of pediatric ESRD. Diabetic nephropathy accounts for
only 0.1% of causes leading to pediatric kidney transplant.
Notes
- This question originally printed in the Pediatric Anesthesiology Review Topics kindle book series, and appears courtesy of Naerthwyn Press, LLC.
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