Which of the following is TRUE regarding glucocorticoids?
a) Glucocorticoids are primarily produced in the zona reticularis.
b) Glucocorticoids increase glucose utilization by cells.
c) Glucocorticoids decrease hepatic gluconeogenesis, lipolysis, and glycogen
synthesis.
d) Glucocorticoids increase secretion of surfactant in fetal lungs.
e) Cortisol increases production of ACTH via a negative feedback loop.
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Answer
Answer d. Glucocorticoids play an important role in surfactant production in
fetal lungs; they may also be administered exogenously to women in preterm
labor to promote surfactant release. Glucocorticoids are produced in the zona
fasiculata, decrease glucose utilization and increase gluconeogenesis (with a net
effect of increased blood glucose), and decrease ACTH and CRH production via
negative feedback.
Notes
- This question originally printed in the Pediatric Anesthesiology Review Topics kindle book series, and appears courtesy of Naerthwyn Press, LLC.
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