TYK146
The context-sensitive half-life of a drug is related to the following factors:
a) Dose
b) Steady-state concentration
c) Distribution and elimination
d) Both B and C
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The context-sensitive half-life of a drug is related to the following factors:
a) Dose
b) Steady-state concentration
c) Distribution and elimination
d) Both B and C
Answer c.
The context-sensitive half-life refers to the half-life of a drug infusion in the context of the duration of infusion and reflects both drug distribution as well as elimination. However, it is independent of dose and concentration.