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[[File: | [[File:Difficult Tracheal Intubation Algorithm.jpg|800px|center|thumb|Figure 2: Difficult tracheal intubation algorithm. Reproduced with kind permission of Association of Paediatric Anaesthetists]] | ||
Table 1. Classification of rigid indirect laryngoscopes | |||
Classification Description of technique Examples | |||
‘Non-guided’ devices Provide an indirect view of larynx but require direction | |||
of tracheal tube towards larynx. | |||
Bullard laryngoscope | |||
Glidescope | |||
Storz DCI Videolaryngoscope | |||
Storz C-MAC laryngoscope | |||
‘Guided’ devices Provide indirect view and act as a conduit for passage | |||
of tracheal tube. | |||
Airtraq | |||
Optical stylets Provide indirect view via rigid or semi-rigid stylet, with | |||
a ‘loaded’ tracheal tube for railroading. | |||
Bonfils and Brambrink | |||
Shikani | |||
Lightwand | |||
Alternate techniques | |||
Traditional laryngoscopes (curved, straight or McCoy levering blades) | |||
give a direct view of the larynx. Alternate techniques use an indirect | |||
approach with flexible or rigid equipment. | |||
• Flexible indirect laryngoscopy, in the form of fibreoptic intubation, | |||
is the established ‘gold standard’ for the management of the | |||
predicted difficult airway in adults (see below). | |||
• New rigid indirect laryngoscopes are available, including in | |||
paediatric sizes. Rigid indirect laryngoscopy has a place in the | |||
unexpected difficult tracheal intubation algorithm. The choice of | |||
device depends on local availability and expertise. | |||
If visualising the larynx is impossible, then an LMA should be inserted. | |||
LMAs provide a clear airway in the vast majority of children. This | |||
allows delivery of ventilation, oxygenation and anaesthetic gases with | |||
a lower risk of gastric insufflation. The LMA may also be used as a conduit for fibreoptic intubation (FOI) where necessary, or in older | |||
children, the specifically designed intubating LMA, may be used. | |||
If LMA insertion fails, then oxygenation and ventilation must be | |||
provided by mask ventilation. | |||
3. Cannot intubate, cannot ventilate (CICV) - ‘rescue | |||
techniques’ | |||
A simple algorithm for the management of ‘cannot intubate, cannot | |||
ventilate’ is given in Figure 3 : Can’t intubate can’t ventilate algorithm. | |||
http://www.apagbi.org.uk/sites/default/files/images/APA3-CICVFINAL. | |||
pdf | |||
Rescue techniques for the CICV situation have been extensively | |||
researched in the adult literature, but their use in paediatric emergencies | |||
is more anecdotal than evidence-based. The choice is between a surgical | |||
or needle (cannula) technique for cricothyroidotomy. The technique | |||
for cannula cricothroidotomy is shown in Figure 3, and for surgical | |||
[[File:CICV_Algorithm.jpg|800px|center|thumb|Figure 3: Can’t intubate can’t ventilate algorithm. Reproduced with kind permission of Association of Paediatric Anaesthetists ]] | [[File:CICV_Algorithm.jpg|800px|center|thumb|Figure 3: Can’t intubate can’t ventilate algorithm. Reproduced with kind permission of Association of Paediatric Anaesthetists ]] | ||
Table 2. Technique for surgical cricothyroidotomy | |||
1. Position the patient so that the neck is fully extended so that the trachea and larynx are pushed forward | |||
2. Locate the cricothyroid membrane and stabilise the trachea | |||
3. With a scalpel blade make a stab incision through the skin and cricothyroid membrane* | |||
4. Insert a tracheal hook or retractor at the lower edge of the incision | |||
5. Pass an appropriately sized tracheal or tracheostomy tube | |||
6. Ventilate patient and assess effectiveness | |||
7. Secure the tube | |||
Arterial forceps, the scalpel blade and tracheal dilators may be used to dilate the orifice | |||
cricothyroidotomy, in Table 2. | |||
Since there is no randomised controlled trial of one technique versus | |||
another, the choice should be determined by local experience and | |||
availability of equipment. This includes utilising the surgeon who may | |||
be more experienced than the anaesthetist. Adult evidence suggests | |||
surgical cricothyroidotomy is preferable, so this is recommended in | |||
older children. | |||
The important factor is that at least one technique is actually attempted | |||
by someone in the CICV situation when the oxygen saturations are | |||
less than 80% and falling and/or the heart rate is decreasing. | |||
The CICV situation is a particular challenge in infants and small | |||
children, due to important anatomical differences: | |||
• The trachea is small, elastic, flaccid and mobile, and so prone to | |||
collapse during insertion of a transtracheal device. | |||
• The cricothyroid membrane is much smaller, with an average size | |||
of only 2.6 x 3mm, smaller than the smallest tracheal tubes. | |||
• It is more difficult to locate the cricothyroid membrane than in | |||
adults due to a differing orientation of the hyoid bone and the | |||
cricoid and thyroid cartilage. This orientation also increases the | |||
chance of laryngeal trauma during cricothyroidotomy. | |||
• It is easier to locate the space between the tracheal rings rather | |||
than the cricothyroid membrane. | |||
Together these factors mean it may be more appropriate in infants | |||
and small children to perform a surgical tracheostomy. | |||
All ‘rescue techniques’ have significant potential for complications so | |||
should only be performed in life threatening situations. Clearly, all the | |||
steps for difficult facemask ventilation should be tried first. If muscle | |||
relaxants have been used and can be reversed, wake the child up. | |||
THE EXPECTED DIFFICULT AIRWAY | |||
If the preoperative airway assessment alerts the anaesthetist to expected | |||
difficulties in airway management then there are three key questions: | |||
1. Does the anaesthetist have the necessary paediatric airway | |||
experience? | |||
2. Does the hospital have the necessary paediatric equipment? | |||
3. Does the relative benefit of the planned surgery outweigh the | |||
possible risks of anaesthesia? | |||
If there is any doubt, full discussion should take place with the parents | |||
(or carers), child, surgeons and anaesthetists. It may be appropriate | |||
for the child to be referred to specialist hospital or wait for a more | |||
experienced paediatric anaesthetist to attend. | |||
The anaesthesia plan must be carefully considered, including what to | |||
do if tracheal intubation is unsuccessful; will the child be woken up, | |||
or will a tracheostomy be necessary. The anaesthesia plan should be | |||
communicated clearly to the whole theatre team including surgeons | |||
and nursing staff. Difficult airway equipment must be checked and | |||
prepared. | |||
The primary plan for management of the expected difficult paediatric | |||
airway will likely be one of the following: | |||
1. Laryngoscopy anticipated to be difficult but may be possible: | |||
Attempt laryngoscopy and intubation. If fails, consider | |||
repositioning and try alternate laryngoscopes if available, or insert | |||
LMA and perform fibreoptic intubation (FOI) via LMA. | |||
2. Laryngoscopy predicted to be impossible: Perform nasal FOI or | |||
insert LMA and perform FOI via LMA. | |||
3. Laryngoscopy and LMA insertion known to be impossible: | |||
perform nasal FOI. | |||
4. Laryngoscopy, LMA insertion and nasal FOI not available | |||
or known to be impossible: perform tracheostomy either using | |||
inhalational anaesthesia via face mask or intravenous ketamine | |||
especially if face mask anaesthesia impossible. | |||
Blind intubation through an LMA is NOT recommended in children | |||
due to risk of airway trauma. Attempts at FOI should be limited to two | |||
and if unsuccessful, consider waking child, or continue with surgical | |||
procedure on an LMA. In situations where LMAs are unavailable, | |||
ventilation by face mask is the alternative. If neither LMAs nor FOI | |||
are available, the surgeon and anaesthetist need to discuss whether | |||
the benefits of surgery outweigh the risk of attempting anaesthesia | |||
in a child with a known difficult airway with insufficient equipment | |||
to provide safe management. This is a very difficult decision and will | |||
depend on the individual merits of each case. | |||
Premedication | |||
The use of sedative premedication in a child with a potential airway | |||
problem is controversial. A frightened, screaming child producing | |||
lots of secretions and in whom it is difficult to place monitoring, | |||
intravenous cannula, and even approach to do an inhalational | |||
induction, is also a risk. | |||
Therefore, a small dose of sedative premedication, such as midazolam | |||
0.3-0.5mg.kg-1 is often appropriate. Atropine is useful as an antisialogue | |||
(30-40 micrograms.kg-1 PO or 20 micrograms.kg-1 IM). Peak effect of | |||
atropine is 90 minutes if given PO, 25 minutes if given IM. | |||
Anaesthetic technique | |||
The most important principle in managing the difficult airway in | |||
children is to maintain spontaneous ventilation until the airway is | |||
secure. | |||
‘Awake’ techniques require good patient co-operation, which is rarely | |||
possible in children. Therefore, the child must be anaesthetised so the | |||
choice is between an inhalational or intravenous technique. The variety | |||
of airway problems encountered in children means the anaesthetic | |||
must be tailored to the individual situation: | |||
• Large extraoral tumours may mean a face mask will not fit | |||
the child’s face, so an inhalational induction is impossible and IV | |||
induction/sedation must be used instead. | |||
• Large intraoral tumours prevent laryngoscopy and the use of an | |||
LMA - nasal fibreoptic intubation (FOI) should be used. | |||
• Conditions such a noma (cancrum oris) often cause severe | |||
limitation of mouth opening - nasal FOI is likely to be required. | |||
• Other problems such as partial mouth opening, severe retrongathia | |||
or bony abnormalities (ameloblastoma) often make laryngoscopy | |||
difficult but do permit the insertion of an LMA if laryngoscopy | |||
proves impossible. | |||
• Burns contractures causing fixed flexion of the neck may be | |||
released prior to intubation using ketamine anaesthesia and with | |||
local infiltration. | |||
The variety of clinical conditions mean a one-size-fits all approach is | |||
impossible. The best technique will depend on the equipment and | |||
expertise available, as well as the nature of the difficult airway. | |||
Inhalational induction, using halothane or sevoflurane in 100% | |||
oxygen, is generally recommended Intravenous access may be | |||
established either before or after induction but must occur before | |||
airway instrumentation. The general technique is to deepen anaesthesia | |||
until laryngoscopy is tolerated or LMA inserted or FOI performed | |||
depending on the airway management plan. | |||
If inhalational induction is impossible, small doses of IV induction | |||
agent should be given to induce loss of consciousness but still | |||
preserving spontaneous ventilation. Propofol 0.5-1mg.kg-1 or ketamine | |||
0.5-1mg.kg-1 should be given and titrated to effect. | |||
If inhalational induction is not possible due to pain, for instance, from | |||
an infected facial mass/tumour (rather than because of a large extraoral | |||
tumour meaning a face mask will not fit), give a small dose of ketamine, | |||
then apply the face mask and deepen anaesthesia by spontaneous | |||
inhalation with sevoflurane or halothane. In our experience, this | |||
combination provides better conditions for laryngoscopy than when | |||
using intravenous ketamine alone. | |||
Nasal fibreoptic intubation – general | |||
• Maintain anaesthesia either with incremental doses of ketamine | |||
or inhalational anaesthesia either via a nasal airway in the other | |||
nostril connected to the breathing circuit or using a specially | |||
designed facemask with a port for insertion of the fibreoptic | |||
bronchoscope. | |||
Table 3. Size compatibility of tracheal tubes, bronchoscopes and LMAs | |||
Tracheal tube size 2.5 3.0 3.5 4 4.5 5 6 | |||
Will fit through classic LMA size: 1 1 1.5 2 2 2.5 3 | |||
Will fit over bronchoscope Outer Diameter: 2.0mm 2.5mm 2.8mm 3.5mm 3.5mm 4.1mm 5mm | |||
Will fit over AEC size: 7F 8F 8F 11F 11F 11F 14F | |||
[Note: different brands of LMA vary in their internal diameter. It is important to determine the compatibility of equipment within your own department.] | |||
• Use a topical vasoconstrictor to prevent bleeding from the nose | |||
during FOI, as otherwise this may make intubation impossible. | |||
Pseudoephedrine, ephedrine, phenylephrine, oxymetazoline, or | |||
nasal packs soaked in 1:10,000 adrenaline may be used, depending | |||
on local availability. | |||
• Apply topical lidocaine to the nose and oropharynx. Larger | |||
fibreoptic laryngoscopes often have a channel through which local | |||
anaesthesia can be injected. Alternatively an epidural catheter can | |||
be passed through the suction port (if present) and local anaesthetic | |||
injected through this. Be careful not to exceed the maximum dose | |||
of lidocaine (3mg.kg-1 i.e. 0.3ml.kg-1 of a 1% solution). | |||
The correct size of tracheal tube is critical to success. Too large a | |||
tube will fail and require the bronchoscope to be withdrawn and the | |||
procedure repeated. Too small may make subsequent positive pressure | |||
ventilation difficult. It is sensible to use a small cuffed tube if available, | |||
rather than repeated bronchoscopy. | |||
Fibreoptic intubation through an LMA | |||
There are three main techniques available: | |||
1. Railroad the tracheal tube over the fibreoptic bronchoscope into | |||
the trachea | |||
2. Railroad an airway exchange catheter (AEC) over the bronchoscope | |||
into the trachea. | |||
3. Pass a soft tip wire through the suction channel of the bronchoscope | |||
into the trachea, then pass an AEC or similar over the wire as a | |||
guide for the tracheal tube. | |||
The choice of technique depends upon size of the child, the size of the | |||
LMA, and the diameter of available bronchoscope (Table 3). Removal | |||
of the LMA once the tracheal tube is in situ may be challenging. | |||
Options include: | |||
• Leave the LMA in situ | |||
• Use a long tracheal tube (croup tube) | |||
• Fix two tracheal tubes together over the FOB; the LMA may be | |||
withdrawn over the tracheal tubes. | |||
• Use an AEC. | |||
Tracheostomy | |||
A tracheostomy should be performed by an experienced practitioner, | |||
normally an ENT surgeon. Inhalational anaesthesia or small | |||
incremental doses of ketamine (as above) may be given to supplement | |||
local infiltration anaesthesia. The child should breathe 100% oxygen | |||
by facemask. | |||
DIFFICULT AIRWAY CART | |||
The equipment available in different institutions will vary considerably. | |||
It is good practice to organise airway equipment in such a way that | |||
it is readily accessible in an emergency. Many hospitals use a ‘difficult | |||
airway cart’ to do this. This is simply a trolley or cart where all the | |||
useful equipment for managing difficult airways is stored according | |||
to the step-wise approach to managing a difficult airway. | |||
For example, using the algorithms presented in this review, the difficult | |||
airway cart could consist of a series of drawers or boxes containing: | |||
Drawer 1: simple laryngoscopes and airway adjuncts. | |||
Drawer 2: alternative laryngoscopes and LMAs. | |||
Drawer 3: equipment for fibreoptic intubation | |||
Drawer 4: equipment for CICV situations. | |||
Whatever the availability and variety of equipment, the difficult airway | |||
cart (or boxes) should always be stored in the same place, close to the | |||
operating rooms, and the contents regularly checked. The cart should | |||
be physically present in the operating room for any child with an | |||
anticipated difficult airway; and can be quickly fetched when faced | |||
with an unexpected problem. | |||
CONCL USION | |||
Unexpected difficult airways in paediatric practice are rare. Many | |||
problems can be prevented by routine pre-operative airway assessment, | |||
pre-oxygenation, and preparation of equipment. A simple step-wise | |||
approach to management improves outcome. Anaesthetists have | |||
a responsibility to be familiar with airway algorithms and make | |||
pragmatic modifications to account for available resources. | |||
== REFERENCES == | == REFERENCES == |