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Which of the following statements is true concerning aspirin? | Which of the following statements is true concerning aspirin? | ||
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D. Aspirin's effects are reversible with administration of FFP | D. Aspirin's effects are reversible with administration of FFP | ||
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==Answer== | ==Answer== | ||
The answer is A. Aspirin's mechanism of action is the interference of synthesis of arachidonic acid. Inhibiting the P2Y12 purinergic receptor involved in platelet activation is the mechanism for clopidigrel (Plavix) and ticlopidine (Ticlid). Aspirin has effects that are IRREVERSIBLE and last longer than 24 hours. The effects of aspirin last for the life of the platelet (between 0-5 days depending on how old the platelet is already). | The answer is A. Aspirin's mechanism of action is the interference of synthesis of arachidonic acid. Inhibiting the P2Y12 purinergic receptor involved in platelet activation is the mechanism for clopidigrel (Plavix) and ticlopidine (Ticlid). Aspirin has effects that are IRREVERSIBLE and last longer than 24 hours. The effects of aspirin last for the life of the platelet (between 0-5 days depending on how old the platelet is already). | ||
==Notes== | ==Notes== | ||
<references /> | <references /> | ||
==Keywords== | ==Keywords== | ||
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[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531005/ Shahani Jagdish Menghraj. Anaesthetic considerations in children with congenital heart disease undergoing non-cardiac surgery. Indian J Anaesth. 2012 Sep-Oct; 56(5): 491–495.] | [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531005/ Shahani Jagdish Menghraj. Anaesthetic considerations in children with congenital heart disease undergoing non-cardiac surgery. Indian J Anaesth. 2012 Sep-Oct; 56(5): 491–495.] | ||
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<p style="text-align: center;">[[TYK About | About Test Your Knowledge]]</p> | <p style="text-align: center;">[[TYK About | About Test Your Knowledge]]</p> | ||