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Perioperative fluids in children: Difference between revisions
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→THE FEAST STUDY
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* Give additional fluids to correct deficits, measured or suspected ongoing losses using 0.9% saline, Hartmanns/ Ringer’s/Plasma-Lyte, colloid or blood as indicated. | * Give additional fluids to correct deficits, measured or suspected ongoing losses using 0.9% saline, Hartmanns/ Ringer’s/Plasma-Lyte, colloid or blood as indicated. | ||
=== | === The FEAST Study === | ||
The FEAST study was a large randomised controlled study carried out in six hospitals in Africa (Kenya, Uganda and Tanzania), published in 2011.<ref name=":0" /> Children aged 2 months to 12 years with a diagnosis of a severe febrile illness (impaired consciousness and/or respiratory distress with impaired perfusion) were randomised to receive a fluid bolus of 20ml.kg<sup>-1</sup> 0.9% saline or 20ml.kg<sup>-1</sup> 5% albumin when they were admitted to hospital, or they were included in a control group and treated with routine maintenance fluids using the‘4,2,1’ rule. More than 3000 children were included in the trial, which is the largest study of its kind in fluid resuscitation in children. Children with gastroenteritis, burns or requiring surgery were NOT included in the study. | The FEAST study was a large randomised controlled study carried out in six hospitals in Africa (Kenya, Uganda and Tanzania), published in 2011.<ref name=":0" /> Children aged 2 months to 12 years with a diagnosis of a severe febrile illness (impaired consciousness and/or respiratory distress with impaired perfusion) were randomised to receive a fluid bolus of 20ml.kg<sup>-1</sup> 0.9% saline or 20ml.kg<sup>-1</sup> 5% albumin when they were admitted to hospital, or they were included in a control group and treated with routine maintenance fluids using the‘4,2,1’ rule. More than 3000 children were included in the trial, which is the largest study of its kind in fluid resuscitation in children. Children with gastroenteritis, burns or requiring surgery were NOT included in the study. | ||