Jump to content

Patent Ductus Arteriosus

From PedsAnesthesiaNet

This is a Stub Notice. This page has not been completed. You can work on this page by signing in and going to the Edit tab. Thanks for helping to make PedsAnesthesia.Net Wiki useful.

Go to the Main Page to see the Topic Outline.

Go to the Generalized Suggested Outline for information on case-specific details for each page.

Go to the Test Page for examples on how to use references in the page.


Relevant Article Depot:


1. Ambalavanan N, Aucott SW, Salavitabar A, Levy VY. Patent Ductus Arteriosus in Preterm Infants. Pediatrics 2025 (In eng). DOI: 10.1542/peds.2025-071425.

2. Shepherd JL, Noori S. What is a hemodynamically significant PDA in preterm infants? Congenit Heart Dis 2019;14(1):21–26. (In eng). DOI: 10.1111/chd.12727.

2b. Zhang, K., Ray, A. M. & DiNardo, J. A. Optimizing Hemodynamic Management in the Neonatal Intensive Care Unit: Leveraging Neonatal Echocardiography. J. Cardiothorac. Vasc. Anesthesia 38, 1630–1633 (2024).

3. Heymann MA, Rudolph AM, Silverman NH. Closure of the ductus arteriosus in premature infants by inhibition of prostaglandin synthesis. NEnglJMed 1976;295(10):530–533.

4. Jasani B, Mitra S, Shah PS. Paracetamol (acetaminophen) for patent ductus arteriosus in preterm or low birth weight infants. The Cochrane database of systematic reviews 2022;12:Cd010061. (In eng). DOI: 10.1002/14651858.CD010061.pub5.

5. Mitra S, Florez ID, Tamayo ME, et al. Association of Placebo, Indomethacin, Ibuprofen, and Acetaminophen With Closure of Hemodynamically Significant Patent Ductus Arteriosus in Preterm Infants: A Systematic Review and Meta-analysis. Jama 2018;319(12):1221–1238. (In eng). DOI: 10.1001/jama.2018.1896.

6. Kuntz MT, Staffa SJ, Graham D, et al. Trend and Outcomes for Surgical Versus Transcatheter Patent Ductus Arteriosus Closure in Neonates and Infants at US Children's Hospitals. J Am Heart Assoc 2022;11(1):e022776. (In eng). DOI: 10.1161/jaha.121.022776.

7. Sathanandam SK, Gutfinger D, O'Brien L, et al. Amplatzer Piccolo Occluder clinical trial for percutaneous closure of the patent ductus arteriosus in patients ≥700 grams. Catheter Cardiovasc Interv 2020;96(6):1266–1276. (In eng). DOI: 10.1002/ccd.28973.

Conrad C, Newberry D. Understanding the pathophysiology, implications, and treatment options of patent ductus arteriosus in the neonatal population. Adv Neonatal Care. 2019 Jun; 19(3): 179-187. PMID: 30720481

Hamrick SE, Hansmann G. Patent ductus arteriosus of the preterm infant. Pediatrics. 2010 May; 125(5): 1020-1030. PMID: 20421261