Appendectomy

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Relevant Article Depot:

Nonoperative management of appendicitis in children

Substantial postoperative pain is common among children undergoing laparoscopic appendectomy

Pediatric laparoscopic appendectomy for acute appendicitis

Anaesthesia and laparoscopic surgery in children

Faria I, Cintra ACG, de Oliveira L, Squizzato F, Maia AS, Cunha AG, Radhakrishnan RS: Reevaluating Nonoperative Management for Pediatric Uncomplicated Acute Appendicitis: A Systematic Review and Meta-Analysis. JAMA pediatrics 2025.

Rangel SJ: Management of Uncomplicated Appendicitis-Moving Past the Superiority Debate. JAMA pediatrics 2025.

Podda M, Gerardi C, Cillara N, Fearnhead N, Gomes CA, Birindelli A, Mulliri A, Davies RJ, Di Saverio S: Antibiotic Treatment and Appendectomy for Uncomplicated Acute Appendicitis in Adults and Children: A Systematic Review and Meta-analysis. Annals of surgery 2019, 270(6):1028–1040.

Brucchi F, Filisetti C, Luconi E, Fugazzola P, Cattaneo D, Ansaloni L, Zuccotti G, Ferraro S, Danelli P, Pelizzo G: Non-operative management of uncomplicated appendicitis in children, why not? A meta-analysis of randomized controlled trials. World J Emerg Surg 2025, 20(1):25.

Huang L, Yin Y, Yang L, Wang C, Li Y, Zhou Z: Comparison of antibiotic therapy and appendectomy for acute uncomplicated appendicitis in children: a meta-analysis. JAMA pediatrics 2017, 171(5):426–434.

Decker E, Ndzi A, Kenny S, Harwood R: Systematic review and meta-analysis to compare the short-and long-term outcomes of non-operative management with early operative management of simple appendicitis in children after the COVID-19 pandemic. Journal of Pediatric Surgery 2024, 59(6):1050–1057.

St Peter SD, Noel-MacDonnell JR, Hall NJ, Eaton S, Suominen JS, Wester T, Svensson JF, Almström M, Muenks EP, Beaudin M: Appendicectomy versus antibiotics for acute uncomplicated appendicitis in children: an open-label, international, multicentre, randomised, non-inferiority trial. The Lancet 2025, 405(10474):233–240.

Adams SE, Perera MRS, Fung S, Maxton J, Karpelowsky J. Non-operative management of uncomplicated appendicitis in children: a randomized, controlled, non-inferiority study evaluating safety and efficacy. ANZ J Surg. 2024 Sep;94(9):1569-1577.

Patkova B, Svenningsson A, Almström M, Eaton S, Wester T, Svensson JF: Nonoperative Treatment Versus Appendectomy for Acute Nonperforated Appendicitis in Children: Five-year Follow Up of a Randomized Controlled Pilot Trial. Annals of surgery 2020, 271(6):1030–1035.

Hall NJ, Sherratt FC, Eaton S, Walker E, Chorozoglou M, Beasant L, Stanton M, Corbett H, Rex D, Hutchings N: Patient-centred outcomes following non-operative treatment or appendicectomy for uncomplicated acute appendicitis in children. BMJ Paediatrics Open 2023, 7(1):e001673.