TYK40
In the infant population, which of the following NMBA is an intermediate acting agent?
A. Atracurium
B. Rocuronium
C. Vecuronium
D. Pancuronium
In the infant population, which of the following NMBA is an intermediate acting agent?
A. Atracurium
B. Rocuronium
C. Vecuronium
D. Pancuronium
The answer is A. Pancuronium is a long acting agent (>50 mins) in any population. While in adults and children rocuronium and vecuronium are intermediate acting agents (20-50 mins), in the infant population these agents have a consistently prolonged duration of action (making them long acting agents in this population). This is due to a longer residence time and a lower site concentration needed for effect (increased sensitivity) in the infant.