Tranexamic Acid

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Relevant Article Depot:

Pharmacokinetics of tranexamic acid after intravenous, intramuscular, and oral routes: a prospective, randomised, crossover trial in healthy volunteers

Update on Applications and Limitations of Perioperative Tranexamic Acid

Tranexamic Acid: Current Knowns and Unknowns

References

1. Goobie, S.M., Patient Blood Management Is a New Standard of Care to Optimize Blood Health. Anesth Analg, 2022. 135(3): p. 443-446.

2. Nellis, M.E., et al., Executive Summary of Recommendations and Expert Consensus for Plasma and Platelet Transfusion Practice in Critically Ill Children: From the Transfusion and Anemia EXpertise Initiative-Control/Avoidance of Bleeding (TAXI-CAB). Pediatr Crit Care Med, 2022. 23(1): p. 34-51.

3. Valentine, S.L., J.M. Cholette, and S.M. Goobie, Transfusion Strategies for Hemostatic Blood Products in Critically Ill Children: A Narrative Review and Update on Expert Consensus Guidelines. Anesth Analg, 2022. 135(3): p. 545-557.

4. Yaster, M., et al., A comparison of nitroglycerin and nitroprusside for inducing hypotension in children: a double-blind study. Anesthesiology, 1986. 65(2): p. 175-179.

5. Patel, P.A., et al., Update on Applications and Limitations of Perioperative Tranexamic Acid. Anesth Analg, 2022. 135(3): p. 460-473.

[https://www.nature.com/articles/srep13458.pdf Tranexamic acid evokes pain by modulating neuronal excitability in the spinal dorsal horn]