Acetaminophen

From PedsAnesthesiaNet

This is a Stub Notice. This page has not been completed. You can work on this page by signing in and going to the Edit tab. Thanks for helping to make PedsAnesthesia.Net Wiki useful.

Go to the Main Page to see the Topic Outline.

Go to the Generalized Suggested Outline for information on case-specific details for each page.

Go to the Test Page for examples on how to use references in the page.


Relevant Article Depot:


Comparison of Oral Loading Dose to Intravenous Acetaminophen in Children for Analgesia After Tonsillectomy and Adenoidectomy: A Randomized Clinical Trial

The therapeutic use of acetaminophen in patients with liver disease

Intravenous Acetaminophen-Induced Hypotension: A Review of the Current Literature

Clinical pharmacokinetics of paracetamol

Acetaminophen pharmacokinetics in infants and children with congenital heart disease

Y-site administration of electrolyte solutions and injectable acetaminophen—A physical compatibility study with combinations frequently used in pediatric intensive care and anesthesia

Perioperative Acetaminophen Dosing in Obese Children

Intravenous versus Oral Acetaminophen for Pain: Systematic Review of Current Evidence to Support Clinical Decision-Making-2

Oral versus intravenous acetaminophen for perioperative pain management in adult patients undergoing non-cardiac surgery: A quantile segmented regression analysis

Plasma concentrations after high-dose (45 mg.kg-1) rectal acetaminophen in children

Interventions for paracetamol (acetaminophen) overdose

Intravenous versus oral acetaminophen for pain and quality of recovery after ambulatory spine surgery: a randomized controlled trial

Mahon RM, Rajbhandari P, Brown TA, Engler LJ, Bhalla T. Improving perioperative acetaminophen administration for safer and cost-effective multimodal analgesia in pediatric surgery: A QI initiative. Paediatr Anaesth. 2024 Apr 5. doi: 10.1111/pan.14893. Epub ahead of print. PMID: 38578161.

Lammers CR, Schwinghammer AJ, Hall B, et al. Comparison of Oral Loading Dose to Intravenous Acetaminophen in Children for Analgesia After Tonsillectomy and Adenoidectomy: A Randomized Clinical Trial. Anesthesia and analgesia 2021;133(6):1568-1576. (In eng). DOI: 10.1213/ane.0000000000005678.

Chisholm AG, Sathyamoorthy M, Seals SR, Carron JD. Does intravenous acetaminophen reduce perioperative opioid use in pediatric tonsillectomy? Am J Otolaryngol 2019;40(6):102294. (In eng). DOI: 10.1016/j.amjoto.2019.102294.

Efficacy of different routes of acetaminophen administration for postoperative pain in children: a systematic review and network meta-analysis

Acetaminophen for Prevention and Treatment of Organ Dysfunction in Critically Ill Patients With Sepsis: The ASTER Randomized Clinical Trial