Local Anesthetic Systemic Toxicity - LAST

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Relevant Article Depot:

Local anesthetic systemic toxicity in children: a review of recent case reports and current literature - an infographic

Update on Local Anesthetic Toxicity, Prevention and Treatment During Regional Anesthesia in Infants and Children

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https://twitter.com/jeffgadsden/status/1449446835911802880?s=21

Local anesthetic systemic toxicity in children: a review of recent case reports and current literature

and hemodynamic changes associated with unintentional intravascular injection of bupivacaine with epinephrine in infants

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The Third American Society of Regional Anesthesia and Pain Medicine Practice Advisory on Local Anesthetic Systemic Toxicity: Executive Summary 2017

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Local anesthetic systemic toxicity in children: a review of recent case reports and current literature

Central nervous system and cardiac effects from long-acting amide local anesthetic toxicity in the intact animal model

Pretreatment or resuscitation with a lipid infusion shifts the dose-response to bupivacaine-induced asystole in rats

Ultrasound guidance reduces the risk of local anesthetic systemic toxicity following peripheral nerve blockade

Local anesthetic systemic toxicity: Continuing Professional Development

Systematic review of the systemic concentrations of local anaesthetic after transversus abdominis plane block and rectus sheath block

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LAST (Local Anesthetic Systemic Toxicity): A practical update for clinicians (Youtube)

Ramesh AS, Boretsky K. Local anesthetic systemic toxicity in children: a review of recent case reports and current literature. Reg Anesth Pain Med 2021;46: 909-914. doi: 10.1136/rapm-2021-102529. PMID: 34099573

Infographic

Gupta RK, Schwenk ES. Local anesthetic systemic toxicity in children: a review of recent case reports and current literature – an infographic. Reg Anesth Pain Med 2021;46: 915. doi: 10.1136/rapm-2021-102993. PMID: 34230193

https://pubmed.ncbi.nlm.nih.gov/14715049/