TYK337
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Which of the following play the greatest role in anaphylactic reactions?
a) Lymphocytes
b) Erythrocytes
c) Histiocytes
d) Eosinophils
e) Dust cells
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Answer
Answer a. Anaphylaxis is mediated by IgE, which is produced by lymphocytes. In addition, histamine and several arachidonic acid metabolites are implicated in anaphylaxis; these are released by tissue mast cells and (to a lesser extent) circulating basophils. Eosinophils target primarily parasites; histiocytes and dust cells are both tissue-bound cells in the monocyte-macrophage lineage.
Notes
- This question originally printed in the Pediatric Anesthesiology Review Topics kindle book series, and appears courtesy of Naerthwyn Press, LLC.