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In the infant population, which of the following NMBA is an intermediate acting agent?
A. Atracurium
B. Rocuronium
C. Vecuronium
D. Pancuronium
The answer is A. Pancuronium is a long acting agent (>50 mins) in any population. While in adults and children rocuronium and vecuronium are intermediate acting agents (20-50 mins), in the infant population these agents have a consistently prolonged duration of action (making them long acting agents in this population). This is due to a longer residence time and a lower site concentration needed for effect (increased sensitivity) in the infant.