TYK288

Anesthetic implications of immature renal function include

a) Renal autoregulation is impaired by inhalational agents

b) Increased compound A production leading to renal failure

c) Prolonged elimination half-life of cephalosporins

d) Prolonged elimination of remifentanil due to increased extracellular fluid volume

e) None of the above

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Answer

Answer c. The elimination half-life of cephalosporins is prolonged. Renal autoregulation is maintained with inhalational agents. Increased risk of renal failure with use of sevoflurane and compound A formation has NOT been demonstrated in infants. Remifentanil metabolism is unaffected by renal or hepatic function.

Notes

This question originally printed in the Pediatric Anesthesiology Review Topics kindle book series, and appears courtesy of Naerthwyn Press, LLC.

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