Opioid Free Techniques: Difference between revisions

Latest revision as of 16:20, 7 January 2026

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Relevant Article Depot:

Bringing Back the Balance: Opioid Reduction in Anesthesia

Outcomes for 41 260 pediatric surgical patients with opioid-free anesthesia: One center's experience.

Evidence for the Efficacy of Systemic Opioid-Sparing Analgesics in Pediatric Surgical Populations: A Systematic Review.

Rational Perioperative Opioid Management in the Era of the Opioid Crisis.

Opioids and Public Health: The Prescription Opioid Ecosystem and Need for Improved Management.

Opioid-free anaesthesia reduces postoperative nausea and vomiting after thoracoscopic lung resection: a randomised controlled trial Association of Intraoperative Opioid Administration With Postoperative Pain and Opioid Use. JAMA surgery 2023;158:854-64.

Intraoperative opioid and non-opioid administration patterns and early postoperative pain: A single-center retrospective longitudinal study. Journal of opioid management 2019;15:389-405.

Opioid-free versus opioid-based anesthesia in pancreatic surgery. BMC Anesthesiol 2022;22:9. Correction

Opioid-free Anesthesia and Analgesia in Clinical Practice: Considerations, Techniques, and Limitations

Opioid-free vs. opioid-inclusive anaesthesia with or without regional anaesthesia for postoperative pain: a systematic review with network meta-analysis of randomised controlled trials

Suzetrigine

Suzetrigine, a Non-Opioid NaV1.8 Inhibitor for Treatment of Moderate-to-Severe Acute Pain: Two Phase 3 Randomized Clinical Trials

Suzetrigine: First in a New Class of Nonopioid Analgesics for Acute Pain

Pharmacology and mechanism of action of suzetrigine, a potent and selective NaV1. 8 pain signal inhibitor for the treatment of moderate to severe pain

Selective inhibition of NaV1. 8 with VX-548 for acute pain

Suzetrigine for acute postoperative pain: a systematic review and meta-analysis of current evidence

Targeting Nav1.8 with the nonopioid antagonist suzetrigine for analgesia: cause for optimism?

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-{Stub Notice}
+{{Stub Notice}}
+[https://pubs.asahq.org/anesthesiology/article/134/4/A17/115448/ Bringing Back the Balance: Opioid Reduction in Anesthesia]
+[https://pubmed.ncbi.nlm.nih.gov/37300350/ Outcomes for 41 260 pediatric surgical patients with opioid-free anesthesia: One center's experience.]
+[https://pubmed.ncbi.nlm.nih.gov/29049110/ Evidence for the Efficacy of Systemic Opioid-Sparing Analgesics in Pediatric Surgical Populations: A Systematic Review.]
+[https://pubmed.ncbi.nlm.nih.gov/32058348/ Rational Perioperative Opioid Management in the Era of the Opioid Crisis.]
+[https://pubmed.ncbi.nlm.nih.gov/34874401/ Opioids and Public Health: The Prescription Opioid Ecosystem and Need for Improved Management.]
+[https://www.bjanaesthesia.org/article/S0007-0912(23)00628-1/fulltext Opioid-free anaesthesia reduces postoperative nausea and vomiting after thoracoscopic lung resection: a randomised controlled trial]
+[https://pubmed.ncbi.nlm.nih.gov/37314800/ Association of Intraoperative Opioid Administration With Postoperative Pain and Opioid Use. JAMA surgery 2023;158:854-64.]
+[https://pubmed.ncbi.nlm.nih.gov/31849030/ Intraoperative opioid and non-opioid administration patterns and early postoperative pain: A single-center retrospective longitudinal study. Journal of opioid management 2019;15:389-405.]
+[https://pubmed.ncbi.nlm.nih.gov/34983396/ Opioid-free versus opioid-based anesthesia in pancreatic surgery. BMC Anesthesiol 2022;22:9.]
+[https://pubmed.ncbi.nlm.nih.gov/35065595/ Correction]
+[https://journals.lww.com/anesthesiology/fulltext/9900/opioid_free_anesthesia_and_analgesia_in_clinical.770.aspx Opioid-free Anesthesia and Analgesia in Clinical Practice: Considerations, Techniques, and Limitations]
+[https://associationofanaesthetists-publications.onlinelibrary.wiley.com/doi/10.1111/anae.70121 Opioid-free vs. opioid-inclusive anaesthesia with or without regional anaesthesia for postoperative pain: a systematic review with network meta-analysis of randomised controlled trials]
+<b>Suzetrigine</b>
+[https://journals.lww.com/anesthesiology/abstract/9900/suzetrigine,_a_non_opioid_nav1_8_inhibitor_for.661.aspx Suzetrigine, a Non-Opioid NaV1.8 Inhibitor for Treatment of Moderate-to-Severe Acute Pain: Two Phase 3 Randomized Clinical Trials]
+[https://journals.lww.com/anesthesiology/fulltext/2025/06000/suzetrigine__first_in_a_new_class_of_nonopioid.11.aspx Suzetrigine: First in a New Class of Nonopioid Analgesics for Acute Pain]
+[https://pubmed.ncbi.nlm.nih.gov/39775738/  Pharmacology and mechanism of action of suzetrigine, a potent and selective NaV1. 8 pain signal inhibitor for the treatment of moderate to severe pain]
+[https://www.nejm.org/doi/full/10.1056/NEJMoa2209870 Selective inhibition of NaV1. 8 with VX-548 for acute pain]
+[https://www.bjanaesthesia.org/article/S0007-0912(25)00375-7/abstract Suzetrigine for acute postoperative pain: a systematic review and meta-analysis of current evidence]
+[https://www.bjanaesthesia.org/article/S0007-0912(25)00468-4/fulltext Targeting Nav1.8 with the nonopioid antagonist suzetrigine for analgesia: cause for optimism?]