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Cerebrospinal fluid is a clear body fluid that occupies the subarachnoid space and the ventricular system of the brain and spinal cord. Cerebrospinal fluid volume at different periods of life is shown in Table 1. | Cerebrospinal fluid is a clear body fluid that occupies the subarachnoid space and the ventricular system of the brain and spinal cord. Cerebrospinal fluid volume at different periods of life is shown in Table 1. | ||
Table 1. CSF volume in children | {| class="wikitable" | ||
|+Table 1. <i>CSF volume in children</i> | |||
| | |||
|'''Cerebrospinal fluid volume (ml.kg(-1))''' | |||
|- | |||
|Neonates | |||
|10 | |||
|- | |||
|Infants less than 15Kg | |||
|4 | |||
|- | |||
|Young Children | |||
|3 | |||
|- | |||
|Adolescent/Adult | |||
|1.5-2 | |||
|} | |||
The volume of distribution of drugs injected into the subarachnoid space is higher in infants and neonates than in adults and consequently the injected dose is relatively greater in infants and neonates. | The volume of distribution of drugs injected into the subarachnoid space is higher in infants and neonates than in adults and consequently the injected dose is relatively greater in infants and neonates. | ||