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Which class of antineoplastic agents is most likely to lead to dilated cardiomyopathy?

a) Alkylating agents

b) Anthracyclines

c) Antimetabolites

d) Anti-mitotic agents

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Answer

Answer b. While nearly all of the antineoplastic therapies may cause lifethreatening complications when administered at high doses, of the choices offered the anthracyclines are most commonly associated with cardiomyopathy.

Notes

This question originally printed in the Pediatric Anesthesiology Review Topics kindle book series, and appears courtesy of Naerthwyn Press, LLC.

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