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Which is a result of failure of proper lateralization of the gut during development?
a) Waardenburg-Shah Syndrome
b) Hirschsprung Disease
c) Lactose intolerance
d) Polysplenia
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Answer
Answer d. Both Waardenburg-Shah Syndrome and Hirschsprung disease are caused by impaired neural development. Lactose intolerance is due to late activation of the enzyme lactase. Polysplenia results from failure of proper lateralization during embryonic development and subsequent situs inversus.
Notes
- This question originally printed in the Pediatric Anesthesiology Review Topics kindle book series, and appears courtesy of Naerthwyn Press, LLC.