TYK401

Which of the following best identifies the site of action of mu-opioid receptors in the central nervous system?

a) Inhibition of neurotransmitter release at the neuromuscular junction

b) Inhibition of neurotransmitter release at the presynaptic terminal

c) Stimulation of neurotransmitter release at the postsynaptic terminal

d) Increased conduction speed in the corticospinal tract

e) Enhanced perception in the thalamus

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Answer

Answer b. Opioid receptors (mu, kappa, and delta) all produce analgesia primarily by inhibiting synaptic transmission in the CNS and in the myenteric plexus via their location on the presynaptic terminal.

Notes

This question originally printed in the Pediatric Anesthesiology Review Topics kindle book series, and appears courtesy of Naerthwyn Press, LLC.

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