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	<updated>2026-04-21T23:17:37Z</updated>
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		<title>metawikimedia&gt;TYK bot: Bot: Automated import of articles</title>
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		<updated>2018-09-16T21:06:46Z</updated>

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&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;__NOTOC__&lt;br /&gt;
Which of the following is true about Hirschsprung’s Disease?&lt;br /&gt;
&lt;br /&gt;
a) Absence of innervation in the mucosa leads to dilation of the affected areas&lt;br /&gt;
&lt;br /&gt;
b) Autonomic dysfunction leads to constriction of the large intestine&lt;br /&gt;
&lt;br /&gt;
c) Toxic megastomach is a feared complication&lt;br /&gt;
&lt;br /&gt;
d) There is an association between Hirschsprung’s disease and Pierre-Robin&lt;br /&gt;
sequence&lt;br /&gt;
&lt;br /&gt;
e) It usually does not require surgical intervention&lt;br /&gt;
&amp;lt;div class=&amp;quot;mw-customtoggle-TYK_Answer&amp;quot; style=&amp;quot;text-align: right; color:#0000ff&amp;quot;&amp;gt;Click for Answer&amp;lt;/div&amp;gt;&lt;br /&gt;
&amp;lt;div class=&amp;quot;mw-collapsible mw-collapsed&amp;quot; id=&amp;quot;mw-customcollapsible-TYK_Answer&amp;quot;&amp;gt;&lt;br /&gt;
==Answer==&lt;br /&gt;
Answer b. Hirschsprung’s disease, or congenital aganglionic megacolon, is a&lt;br /&gt;
disease of absence of autonomic ganglia in the colon. It may affect a short&lt;br /&gt;
segment or the entire colon. Importantly, the affected area tends to constrict&lt;br /&gt;
tightly, leading to development of megacolon (or with bacterial overgrowth, toxic&lt;br /&gt;
megacolon) in the segment proximal to the affected area without intervention.&lt;br /&gt;
There is an association between this condition and trisomy 21, Waardenburg&lt;br /&gt;
syndrome, and other genetic anomalies; there is no known association with the&lt;br /&gt;
Pierre-Robin sequence.&lt;br /&gt;
==Notes==&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;br /&gt;
:This question originally printed in the [http://www.amazon.com/Justin-L.-Lockman/e/B00FLG5AEE/ref=ntt_dp_epwbk_0 Pediatric Anesthesiology Review Topics] kindle book series, and appears courtesy of Naerthwyn Press, LLC.&lt;br /&gt;
==Keywords==&lt;br /&gt;
:&lt;br /&gt;
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&amp;lt;p style=&amp;quot;text-align: center;&amp;quot;&amp;gt;[[TYK273|&amp;lt;Prev Question]] --- [[TYK275|Next Question&amp;gt;]]&amp;lt;/p&amp;gt;&lt;br /&gt;
&amp;lt;p style=&amp;quot;text-align: center;&amp;quot;&amp;gt;[[TYK About | About Test Your Knowledge]]&amp;lt;/p&amp;gt;&lt;/div&gt;</summary>
		<author><name>metawikimedia&gt;TYK bot</name></author>
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