TYK23 - Revision history

WikiSysop at 23:14, 22 January 2022

2022-01-22T23:14:32Z

← Older revision		Revision as of 23:14, 22 January 2022
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	The unique advantage of rocuronium over other intermediate duration non-depolarizing muscle relaxants (NDMR) is which of the following?		The unique advantage of rocuronium over other intermediate duration non-depolarizing muscle relaxants (NDMR) is which of the following?

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	E. Lack of potentiation with aminoglycoside antibiotics		E. Lack of potentiation with aminoglycoside antibiotics
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	==Answer==		==Answer==

	The answer is C. The first two letters of the name rocuronium stands for '''rapid onset'''. Of the intermediate duration nondepolarizing muscle relaxants, it has the most rapid onset of action at clinical dosages. Rocuronium has a similar duration of action to vecuronium,		The answer is C. The first two letters of the name rocuronium stands for '''rapid onset'''. Of the intermediate duration nondepolarizing muscle relaxants, it has the most rapid onset of action at clinical dosages. Rocuronium has a similar duration of action to vecuronium,
	atracurium, and cisatracurium. At an ED95 dose (0.3 mg/kg), the onset time is 1.5 to 3 minutes, whereas with		atracurium, and cisatracurium. At an ED95 dose (0.3 mg/kg), the onset time is 1.5 to 3 minutes, whereas with
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	[http://www.drugbank.ca/drugs/DB00728 Rocuronium (DrugBank)]		[http://www.drugbank.ca/drugs/DB00728 Rocuronium (DrugBank)]

	==Keywords==		==Keywords==
	:
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WikiSysop: 1 revision imported

2021-03-05T02:34:42Z

1 revision imported

← Older revision	Revision as of 02:34, 5 March 2021
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metawikimedia>JustinHamrick at 21:58, 2 March 2015

2015-03-02T21:58:38Z

New page

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The unique advantage of rocuronium over other intermediate duration non-depolarizing muscle relaxants (NDMR) is which of the following?

A. Ultra short duration of action

B. Metabolism by plasma pseudocholinesterase

C. More rapid onset of action

D. Lack of need for reversal

E. Lack of potentiation with aminoglycoside antibiotics

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==Answer==

The answer is C. The first two letters of the name rocuronium stands for '''rapid onset'''. Of the intermediate duration nondepolarizing muscle relaxants, it has the most rapid onset of action at clinical dosages. Rocuronium has a similar duration of action to vecuronium,
atracurium, and cisatracurium. At an ED95 dose (0.3 mg/kg), the onset time is 1.5 to 3 minutes, whereas with
the other intermediate nondepolarizing muscle relaxants, the onset time is 3 to 7 minutes. At larger doses
(i.e., 2xED95 or 0.6 mg/kg), onset time can be reduced to 1 to 1.5 minutes

==Notes==
<references />
Lambertus van den Broek, MD∗, MD J.Mar K.H. Wierda, PhD, †, Nicky J. Smeulers, MD‡, Gert Jan van Santen§, Monique G.L. Leclercq§, MD Pim J. Hennis, PhD‖ Clinical pharmacology of rocuronium (ORG 9426): Study of the time course of action, dose requirement, reversibility, and pharmacokinetics [http://www.sciencedirect.com/science/article/pii/0952818094900752 Journal of Clinical Anesthesia Volume 6, Issue 4, July–August 1994, Pages 288–296]

[http://www.drugbank.ca/drugs/DB00728 Rocuronium (DrugBank)]

==Keywords==
:
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