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Side effects of succinylcholine (1 mg/kg IV) administration include all of the
following EXCEPT:

a) Hyperkalemia

b) Increased intraocular pressure

c) Prolonged neuromuscular blockade in patients with a low dibucaine number
(<20)

d) Prolonged neuromuscular blockade in patients with a high dibucaine number
(>80)

e) Myoglobinuria

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==Answer==
Answer d.

Succinylcholine is the only drug in its class still in use in the modern
era; it has the benefits of rapid onset and short duration of action, but is fraught
with unintended effects, including dysrhythmias, muscle breakdown,
myoglobinuria, and hyperkalemia, risk of malignant hyperthermia, increased
intraocular pressure and others. In addition, its pharmacokinetics depend on
pseudocholinesterase for removal from the neuromuscular junction; patients
with a low dibucaine number (< 20) may have prolonged (hours) paralysis after a
single dose. On the other hand, even patients with normal pseudocholinesterase
function (dibucaine number > 80) may have prolonged blockade with a dose of 4-
6 mg/kg (or repeated doses in short succession).
==Notes==
<references />
:This question originally printed in the [http://www.amazon.com/Justin-L.-Lockman/e/B00FLG5AEE/ref=ntt_dp_epwbk_0 Pediatric Anesthesiology Review Topics] kindle book series, and appears courtesy of Naerthwyn Press, LLC.

==Keywords==
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WikiSysop: 1 revision imported

metawikimedia>DrBobGreenberg at 00:12, 11 February 2016