Neuromuscular Blockade - Revision history

WikiSysop at 14:39, 13 April 2026

2026-04-13T14:39:38Z

← Older revision		Revision as of 14:39, 13 April 2026
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	[https://journals.lww.com/anesthesiology/fulltext/2025/08000/sugammadex_for_reversal_of_neuromuscular_blockade.17.aspx Sugammadex for Reversal of Neuromuscular Blockade in Neonates and Infants Less than 2 Years Old: Results from a Phase IV Randomized Clinical Trial]		[https://journals.lww.com/anesthesiology/fulltext/2025/08000/sugammadex_for_reversal_of_neuromuscular_blockade.17.aspx Sugammadex for Reversal of Neuromuscular Blockade in Neonates and Infants Less than 2 Years Old: Results from a Phase IV Randomized Clinical Trial]

			Wachtendorf LJ, Kaiser L, Ahrens E, Tenge T, Riesemann S, Xu X, Shay D, von Wedel D, Paschold BS, Chen G et al: Changes in Intraoperative Rocuronium Dosing after the Introduction of Sugammadex and Association with Postoperative Respiratory Complications: A Retrospective Cohort Study. Anesthesiology 2026, 144(3):597–610.

			Brown SES, Cassidy R, Zhao X, Nause-Osthoff R, Wade M, Wagner D, Haydar B, Chimbira W, Kheterpal S, Colquhoun DA: Impact of Sugammadex Introduction on Using Neuromuscular Blockade and Endotracheal Intubation in a Pediatric Hospital: A Retrospective, Observational Cross-Sectional Study. Anesthesia and analgesia 2025, 140(3):539–549.

			Brown SES, Spellman K, Cassidy R, Nause-Osthoff R, Bailey M, Mentz G, Wagner D, Haydar B, Chimbira W, Kheterpal S et al: A retrospective observational cross-sectional study of intraoperative neuromuscular blocking agent choice and dosing in a US paediatric referral hospital before and after introduction of sugammadex(☆). British journal of anaesthesia 2023, 131(4):e117–e120.

			Faulk DJ, Austin TM, Thomas JJ, Strupp K, Macrae AW, Yaster M: A Survey of the Society for Pediatric Anesthesia on the Use, Monitoring, and Antagonism of Neuromuscular Blockade. Anesthesia and analgesia 2021, 132(6):1518–1526.

			Kotake Y, Ochiai R, Suzuki T, Ogawa S, Takagi S, Ozaki M, Nakatsuka I, Takeda J: Reversal with sugammadex in the absence of monitoring did not preclude residual neuromuscular block. Anesthesia and analgesia 2013, 117(2):345–351.

			Scheffenbichler FT, Rudolph MI, Friedrich S, Althoff FC, Xu X, Spicer AC, Patrocínio M, Ng PY, Deng H, Anderson TA et al: Effects of high neuromuscular blocking agent dose on post-operative respiratory complications in infants and children. Acta anaesthesiologica Scandinavica 2020, 64(2):156–167.

			Salaün JP, Décary E, Veyckemans F: Recurarisation after sugammadex in children: review of case reports and recommendations. British journal of anaesthesia 2024, 132(2):410–414.

			Veyckemans F, Debouche S, Kaufmann J, Disma N, Amigoni A, Bonatti G, Christensen MI, Engelhardt T, Fuchs A, Fuchs-Buder T et al: 2025 ESAIC and ESPA Guidelines on neuromuscular block in anaesthetised children: Indications, monitoring and reversal. European journal of anaesthesiology 2026, 43(4):295–323.

WikiSysop at 20:32, 6 April 2026

2026-04-06T20:32:11Z

← Older revision		Revision as of 20:32, 6 April 2026
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	6. Gera S, Dali JS, Sharma KR, Garg R, Arya M. Evaluation of intubating conditions in children after sevoflurane induction using propofol or rocuronium bromide--a randomised, prospective, double blind study. Acta Anaesthesiol Belg. 2015;66(4):25-30.		6. Gera S, Dali JS, Sharma KR, Garg R, Arya M. Evaluation of intubating conditions in children after sevoflurane induction using propofol or rocuronium bromide--a randomised, prospective, double blind study. Acta Anaesthesiol Belg. 2015;66(4):25-30.

			Wachtendorf LJ, Kaiser L, Ahrens E, Tenge T, Riesemann S, Xu X, Shay D, von Wedel D, Paschold BS, Chen G et al: Changes in Intraoperative Rocuronium Dosing after the Introduction of Sugammadex and Association with Postoperative Respiratory Complications: A Retrospective Cohort Study. Anesthesiology 2026, 144(3):597–610.

			3. Brown SES, Cassidy R, Zhao X, Nause-Osthoff R, Wade M, Wagner D, Haydar B, Chimbira W, Kheterpal S, Colquhoun DA: Impact of Sugammadex Introduction on Using Neuromuscular Blockade and Endotracheal Intubation in a Pediatric Hospital: A Retrospective, Observational Cross-Sectional Study. Anesthesia and analgesia 2025, 140(3):539–549.

			4. Fuchs-Buder T, Romero CS, Lewald H, Lamperti M, Afshari A, Hristovska AM, Schmartz D, Hinkelbein J, Longrois D, Popp M et al: Peri-operative management of neuromuscular blockade: A guideline from the European Society of Anaesthesiology and Intensive Care. European journal of anaesthesiology 2023, 40(2):82–94.

			5. Thilen SR, Weigel WA, Todd MM, Dutton RP, Lien CA, Grant SA, Szokol JW, Eriksson LI, Yaster M, Grant MD et al: 2023 American Society of Anesthesiologists Practice Guidelines for Monitoring and Antagonism of Neuromuscular Blockade: A Report by the American Society of Anesthesiologists Task Force on Neuromuscular Blockade. Anesthesiology 2023, 138(1):13–41.

WikiSysop at 20:19, 3 March 2026

2026-03-03T20:19:43Z

← Older revision		Revision as of 20:19, 3 March 2026
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	<b>Standards/Guidelines</b>		<b>Standards/Guidelines</b>

			[https://pubmed.ncbi.nlm.nih.gov/41766420/ 2025 ESAIC and ESPA Guidelines on neuromuscular block in anaesthetised children: Indications, monitoring and reversal]

	[https://pubmed.ncbi.nlm.nih.gov/36520073/ 2023 American Society of Anesthesiologists Practice Guidelines for Monitoring and Antagonism of Neuromuscular Blockade: A Report by the American Society of Anesthesiologists Task Force on Neuromuscular Blockade]		[https://pubmed.ncbi.nlm.nih.gov/36520073/ 2023 American Society of Anesthesiologists Practice Guidelines for Monitoring and Antagonism of Neuromuscular Blockade: A Report by the American Society of Anesthesiologists Task Force on Neuromuscular Blockade]

WikiSysop at 20:32, 8 February 2026

2026-02-08T20:32:46Z

← Older revision		Revision as of 20:32, 8 February 2026
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	[https://pubmed.ncbi.nlm.nih.gov/37027807/ A Dose-finding Study of Sugammadex for Reversal of Rocuronium in Cardiac Surgery Patients and Postoperative Monitoring for Recurrent Paralysis]		[https://pubmed.ncbi.nlm.nih.gov/37027807/ A Dose-finding Study of Sugammadex for Reversal of Rocuronium in Cardiac Surgery Patients and Postoperative Monitoring for Recurrent Paralysis]

			[https://journals.lww.com/anesthesiology/fulltext/2025/08000/sugammadex_for_reversal_of_neuromuscular_blockade.17.aspx Sugammadex for Reversal of Neuromuscular Blockade in Neonates and Infants Less than 2 Years Old: Results from a Phase IV Randomized Clinical Trial]

WikiSysop at 22:28, 19 January 2026

2026-01-19T22:28:33Z

← Older revision		Revision as of 22:28, 19 January 2026
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	Curare		Curare



			-----
			1. Vanlinthout LE, Driessen JJ, Stolker RJ, Lesaffre EM, Berghmans JM, Staals LM: Effect of neuromuscular blocking agents on tracheal intubation quality in paediatric patients: a systematic review using network meta-analysis and meta-regression. British journal of anaesthesia 2025, 135(6):1787–1802.

			2. Martyn JAJ, Richtsfeld M, Warner DO: Succinylcholine-induced hyperkalemia in acquired pathologic states: etiologic factors and molecular mechanisms. Anesthesiology 2006, 104(1):158–169.

			3. Lerman J: Perioperative management of the paediatric patient with coexisting neuromuscular disease. British journal of anaesthesia 2011, 107 Suppl 1:i79–89.

			4. Park S, Kim JH, Bae JC, Lee JR, Kim MS. Tracheal intubation with or without a neuromuscular blocking agent for a short surgical procedure in children: Prospective, randomized, double-blind trial. Paediatr Anaesth. 2021 Aug;31(8):863-870.

			5. Viby-Mogensen J, Engbaek J, Eriksson LI, Gramstad L, Jensen E, Jensen FS, Koscielniak-Nielsen Z, Skovgaard LT, Ostergaard D. Good clinical research practice (GCRP) in pharmacodynamic studies of neuromuscular blocking agents. Acta Anaesthesiol Scand. 1996 Jan;40(1):59-74.

			6. Gera S, Dali JS, Sharma KR, Garg R, Arya M. Evaluation of intubating conditions in children after sevoflurane induction using propofol or rocuronium bromide--a randomised, prospective, double blind study. Acta Anaesthesiol Belg. 2015;66(4):25-30.

WikiSysop at 12:34, 19 January 2026

2026-01-19T12:34:45Z

← Older revision		Revision as of 12:34, 19 January 2026
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	[https://link.springer.com/article/10.2165/00003088-200443020-00001 Antiepileptic-Induced Resistance to Neuromuscular Blockers: Mechanisms and Clinical Significance]		[https://link.springer.com/article/10.2165/00003088-200443020-00001 Antiepileptic-Induced Resistance to Neuromuscular Blockers: Mechanisms and Clinical Significance]

			Vanlinthout LE, Driessen JJ, Stolker RJ, Lesaffre EM, Berghmans JM, Staals LM. Effect of neuromuscular blocking agents on tracheal intubation quality in paediatric patients: a systematic review using network meta-analysis and meta-regression. Br J Anaesth. 2025 Dec;135(6):1787-1802. doi: 10.1016/j.bja.2025.08.036. Epub 2025 Oct 10. PMID: 41076411.


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	[https://journals.lww.com/anesthesiology/fulltext/2025/08000/skin_injury_after_removal_of_electrode_used_for.26.aspx Skin Injury after Removal of Electrode Used for Quantitative Monitoring of Neuromuscular Transmission]		[https://journals.lww.com/anesthesiology/fulltext/2025/08000/skin_injury_after_removal_of_electrode_used_for.26.aspx Skin Injury after Removal of Electrode Used for Quantitative Monitoring of Neuromuscular Transmission]


	<b>Agents</b>		<b>Agents</b>
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	Elkhateb R, Campbell DL, Zhao X, et al. Neuromuscular blockade and antagonism in patients with renal impairment: a multicenter retrospective cross-sectional study. Anesthesiology. 2025 Jun; 142(6): 1009-1024. PMID: 39928534		Elkhateb R, Campbell DL, Zhao X, et al. Neuromuscular blockade and antagonism in patients with renal impairment: a multicenter retrospective cross-sectional study. Anesthesiology. 2025 Jun; 142(6): 1009-1024. PMID: 39928534


	Vecuronium		Vecuronium
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	Sugammadexand Women, Hormonal Regulation, and Contraceptives,		<b>Sugammadexand Women, Hormonal Regulation, and Contraceptives</b>

	[https://associationofanaesthetists-publications.onlinelibrary.wiley.com/doi/10.1111/anae.15902 A prospective observational study of the effects of sugammadex on peri-operative oestrogen and progesterone levels in women who take hormonal contraception]		[https://associationofanaesthetists-publications.onlinelibrary.wiley.com/doi/10.1111/anae.15902 A prospective observational study of the effects of sugammadex on peri-operative oestrogen and progesterone levels in women who take hormonal contraception]
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	[https://pubmed.ncbi.nlm.nih.gov/41238516/ Sugammadex hypersensitivity: a national retrospective cohort study from the French pharmacovigilance database]		[https://pubmed.ncbi.nlm.nih.gov/41238516/ Sugammadex hypersensitivity: a national retrospective cohort study from the French pharmacovigilance database]


	<b>Historic</b>		<b>Historic</b>

	Gallamine		Gallamine


	Micacurium		Micacurium

WikiSysop at 13:52, 18 November 2025

2025-11-18T13:52:26Z

← Older revision		Revision as of 13:52, 18 November 2025
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	[https://www.bjanaesthesia.org/article/S0007-0912(25)00284-3/fulltext Incidence of immediate hypersensitivity to sugammadex in Aotearoa New Zealand: a retrospective cohort study]		[https://www.bjanaesthesia.org/article/S0007-0912(25)00284-3/fulltext Incidence of immediate hypersensitivity to sugammadex in Aotearoa New Zealand: a retrospective cohort study]

			[https://pubmed.ncbi.nlm.nih.gov/41238516/ Sugammadex hypersensitivity: a national retrospective cohort study from the French pharmacovigilance database]

	<b>Historic</b>		<b>Historic</b>

WikiSysop at 18:35, 4 October 2025

2025-10-04T18:35:17Z

← Older revision		Revision as of 18:35, 4 October 2025
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	[[TYK6 \|Test Your Knowledge]]: unique advantage of rocuronium		[[TYK6 \|Test Your Knowledge]]: unique advantage of rocuronium

			Elkhateb R, Campbell DL, Zhao X, et al. Neuromuscular blockade and antagonism in patients with renal impairment: a multicenter retrospective cross-sectional study. Anesthesiology. 2025 Jun; 142(6): 1009-1024. PMID: 39928534

	Vecuronium		Vecuronium

WikiSysop at 22:52, 25 September 2025

2025-09-25T22:52:04Z

Show changes

WikiSysop at 22:27, 25 September 2025

2025-09-25T22:27:44Z

← Older revision		Revision as of 22:27, 25 September 2025
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	Rocuronium		Rocuronium

	[https://pubmed.ncbi.nlm.nih.gov/9054273/~~][[TYK6 \|~~Intramuscular rocuronium]]		[https://pubmed.ncbi.nlm.nih.gov/9054273/ Intramuscular rocuronium]

	[https://pubmed.ncbi.nlm.nih.gov/9366462/~~][[TYK6 \|~~Bioavailability of intramuscular rocuronium in infants and children]]		[https://pubmed.ncbi.nlm.nih.gov/9366462/ Bioavailability of intramuscular rocuronium in infants and children]

	[https://pubs.asahq.org/anesthesiology/article/139/1/A16/138250/Goldilocks-and-the-Three-Rocuronium-Reversals-A Goldilocks and the Three Rocuronium Reversals: A Sugammadex Dose-finding Study]		[https://pubs.asahq.org/anesthesiology/article/139/1/A16/138250/Goldilocks-and-the-Three-Rocuronium-Reversals-A Goldilocks and the Three Rocuronium Reversals: A Sugammadex Dose-finding Study]



	[[TYK6 \|Test Your Knowledge]]: unique advantage of rocuronium		[[TYK6 \|Test Your Knowledge]]: unique advantage of rocuronium